Pyridoxine induces non-specific EEG alterations in infants with therapy resistant seizures

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Pyridoxine induces non-specific EEG alterations in infants with therapy resistant seizures

PURPOSE In infants with frequent therapy resistant seizures (TRS-infants), clinical detection of pyridoxine-dependency (PD) or -responsiveness (PR) occurs by empirical intravenous (IV) pyridoxine administration during recording of the EEG. However, in undiagnosed TRS-infants it is still unclear to what extent EEG alterations by pyridoxine-IV are attributable to PD/PR or to non-specific response...

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[Pyridoxine dependent seizures].

Pyridoxine dependent seizures is a rare autosomal recessive disorder. Its manifestations are intractable epilepsy leading to death in status epilepticus. Treatment with pyridoxine prevents the seizures and normalizes the EEG. Early diagnosis is important for the intellectual outcome. In Denmark, the disease has occurred in a child of healthy Tamil immigrants, who are first cousins. The child's ...

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Neglected Atypical Pyridoxine Dependent Seizures

Omid Yaghini, MD; Mohammad-Amir Shahkarami*, MD; Somayeh Shamsaii, MD Pediatrics Department, Isfahan University of Medical Sciences, Isfahan, IR Iran Received: Nov 02, 2009; Accepted: Mar 13, 2010 Vitamin B6 (pyridoxine) dependent seizure (PDS) is an autosomal-recessively inherited disorder which starts within a few hours of birth or even earlier, and can cause intrauterine seizures[1,2]. It oc...

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Intravenous therapy and EEG monitoring in prolonged seizures.

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ژورنال

عنوان ژورنال: Seizure

سال: 2007

ISSN: 1059-1311

DOI: 10.1016/j.seizure.2007.02.008